SLEEP, IMMUNITY AND VACCINE EFFICACY IN DISEASE PREVENTION

Abstract

Sleep is crucial for health and strengthens the immune system, aiding the body in fighting diseases. Research indicates that adequate and quality sleep enhances vaccine efficacy by boosting immune responses, increasing antibody production, and preventing the spread of pathogens. To understand the role and mechanism of sleep in vaccine effectiveness, we searched and screened over 2,000 open-access articles on PubMed and Scopus using relevant keywords following the PRISMA guidelines. Results showed that 7 or more hours of sleep each night increase antibody titers and improve vaccine efficacy and immune memory. Thus, it is essential to focus on enhancing sleep quality and provide appropriate recommendations in vaccination strategies to help care for, protect health, and control epidemics in the community