RESEARCH ON THE SYNTHESIS AND METABOLISM OF SOME 4,6-ARYLPYRIMIDINE-2(1H)-THIONE CONTAINING PROPARGYL GROUP

Abstract

The synthesis of nitrogen-containing heterocycles is receiving much attention from organic synthesizers due to their diverse biological activities. Heterocycles are present in the structure of many natural compounds and play an important role in life. In this paper, we performed click reactions to synthesize some compounds containing both pyrimidine heterocycles and 1,2,3-triazole attached to a D-glucose ring. These types of compounds are predicted to have biological activities derived from two heterocycles, and can be tested or applied in drug production research