EVALUATING THE EFFECTIVENESS OF COMBINED METHOD TO TREAT SYPHACIA OBVELATA PINWORM ON WHITE MICE USING IVERMECTIN 0.1%

Abstract

The experimental descriptive research was conducted on a group of twelve white mice aged 3-4 weeks which consisted of six male individuals and six female individuals, and another group of five 15-20 day pregnant mice. All mice individuals were checked for pinworm infection (+) before being put into the experiment. In this study, mice were allowed to drink Ivermectin 0.1% solution freely once for 24 hours. Then, we sprayed mice and the animal cages directly 3 times with Ivermectin 0.1% solution at the interval of one week. The results showed that the presence of worms and worm eggs was no longer detected in mice during and after 4 months, including both experimental and new-born individuals. There were no adverse effects following the drug administration observed in the experimental individuals and the reproductive performance of pregnant mice. Based on such potential method, we could establish and develope a preventive and curative treatment procedure at experimental mouse breeding facilities to improve the quality of experimental animals.