Testing and Monitoring some Pathogenic Microorganisms in Laboratory Animals by Culture Method
DOI:
https://doi.org/10.56086/jcvb.v2i1.21Keywords:
Testing microorganism, experimental ICR mice, experimental guinea pigAbstract
Background/Purpose: For the purpose of developing routine procedures and monitoring
the quality of laboratory animals at NICVB, the testing and monitoring of some microbial
agents as recommended by the World Health Organization (WHO), using guidelines of the
Federation of European Laboratory Animal Science Associations (FELASA), are cultured
and identified using the BD Phoenix M50 microbial identifier.
Methods: Empirical description research in the laboratory.
Results: The results of testing and monitoring some bacterial pathogens on 100 guinea
pigs before the test and 100 mice before the trial from March 2021 to December 2021
showed that only Staphylococcus aureus bacteria were detected with infection rate of 26%
for ICR mice and 24% for guinea pigs. Thus, the quality of laboratory animals at NICVB
ensures standards to provide for the testing of vaccines and medical biological products.
Conclusion: The quality of laboratory animals raised at NICVB meets the standards for testing
and quality control of vaccines and medical biological products.
