A STUDY ON ANTIBACTERIAL EFFECTS, POLYPHENOL CONTENTS AND ANTIOXIDANT ACTIVITIES OF EXTRACTS FROM PLUCHEA INDICA
DOI:
https://doi.org/10.56086/jcvb.v4i1.143Keywords:
Pluchea Indica, extract, antibacterial effects, polyphenol, antioxidant activityAbstract
Our study investigated antibacterial effects of extracts from Pluchea Indica on gram positive and negative bacteria, including Bacillus subtilis (B. subtilis) ATCC 6633, Staphylococcus aureus (S. aureus) ATCC 25923, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 9027 and Salmonella typhymurium ATCC 13311. In addition, we also measured polyphenol contents and antioxidant activities, applying Folin Ciocalteu and 1,1-diphenyl-2-picrylhydrazyl (DPPH) reagents. Extracts from 6 solvents, including hot water, ethanol, methanol, ethyl acetate, acetone and hexane were used. Experiments were performed in Laboratory of Pharmacology research and Drug development, Center of Research excellence and Innovation, Vietnam National University of Agriculture, from October 2023 to February, 2024. The results showed that Pluchea Indica exerted inhibition on gram positive bacteria, including B. subtilis and S. aureus, and also contained polyphenol and antiosidant activities at significant levels. It confirms the potentials of applying this plant as a natural therapy for bacteria infections. In 6 investigated solvents, methanol showed the best extracting efficacies, in all of 3 parameters, inclusing antibacterial properties, polyphenol contents and antioxidant activities. These results suggest that this solvent should be further studied to explore the potentials of Pluchea Indica and make use of this material in practice.
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